RESUMO
No disponible
Assuntos
Criança , Feminino , Humanos , Masculino , Hiperplasia/metabolismo , Hiperplasia/patologia , Nodularia/citologia , Nodularia/genética , Hepatopatias/genética , Anticoncepcionais Orais/administração & dosagem , Fibrose/metabolismo , Biópsia/métodos , Hiperplasia/complicações , Hiperplasia/genética , Nodularia/classificação , Nodularia/metabolismo , Hepatopatias/metabolismo , Anticoncepcionais Orais , Fibrose/patologia , Biópsia/instrumentaçãoRESUMO
Se describen las características clínicas, diagnósticas, terapéuticas y de investigación en el paciente oncológico pediátrico. Se revisan los efectos secundarios, su detección y prevención (AU)
We describe the clinical, diagnostic, therapeutic and research characteristics in the pediatric oncologic patient. Side eHects, their detection and prevention are reviewed (AU)
Assuntos
Criança , Feminino , Humanos , Masculino , Seguro de Assistência de Longo Prazo/normas , Assistência de Longa Duração/organização & administração , Assistência de Longa Duração/normas , Neoplasias/epidemiologia , Neoplasias/prevenção & controle , Tratamento Farmacológico/métodos , Tratamento Farmacológico/normas , Sobreviventes/estatística & dados numéricos , Efeitos Colaterais e Reações Adversas Relacionados a Medicamentos/prevenção & controle , Seguimentos , Oncologia/organização & administração , Oncologia/normas , /organização & administração , Neoplasias/cirurgia , Neoplasias/complicaçõesRESUMO
La histiocitosis de células de Langerhans (HCL) es una enfermedad poco frecuente, que en muy pocos casos se ha descrito asociada a algunas enfermedades malignas, como la enfermedad de Hodgkin (EH). La afectación del sistema nervioso central (SNC) por la EH se presenta con baja frecuencia, generalmente limitada a los casos de enfermedad avanzada y recurrente. Describimos el caso de un niño que desarrolló estas dos raras circunstancias: por un lado, la coexistencia de la EH y la HCL y, por otro, la recaída de la EH en el SNC (AU)
Langerhans cell histiocytosis (LCH) is a rare disease in children and in a few cases has been described associated to some malignancies like Hodgkins disease (HD). Central nervous system (CNS) involvement in HD has been observed in few cases with systemic and recurrent diseases. We report a case of a child who developed these two rare clinical conditions, the coexistence of HD and LCH and the relapse of HD in CNS (AU)
Assuntos
Criança , Humanos , Masculino , Histiocitose de Células de Langerhans/etiologia , Doença de Hodgkin/patologia , Sistema Nervoso Central/patologia , Histiocitose de Células de Langerhans/terapia , Doença de Hodgkin/terapia , BiópsiaRESUMO
BACKGROUND: Skin diseases are mentioned as a frequent finding in the obese patient. However, to our knowledge no study has been done on this subject. OBJECTIVE: To determine the prevalence of skin diseases associated with different obesity grades and if any dermatosis can be considered an obesity marker. MATERIALS AND METHODS: A cross-sectional study of 156 obese patients who were 110% to 293% overweight were included. Complete medical history and dermatological examination were done. RESULTS: In the 126 female and 30 male obese patients, grades I to V, with a body mass index (BMI) of 27-51, cutaneous findings with statistical significance for linear trend were: plantar hyperkeratosis 54 patients p = 0.00001; acanthosis nigricans 46 patients p = 0.00005; striae 67 patients p = 0.03; skin tags 69 patients p = 0.01; keratosis pilaris 33 patients p = 0.007. Patients with plantar hyperkeratosis were distributed in the obesity groups as follows: grade I = 3 patients; grade II = 7 patients; grade III = 8 patients; grade IV = 17 patients; and grade V = 19 patients. Of the 76 diabetic patients, 26 had acanthosis nigricans, 38 had skin tags, and 27 had plantar hyperkeratosis. DISCUSSION: Plantar hyperkeratosis should be considered as a cutaneous stigma of severe obesity. This is probably a result of pressure directly related to the excess weight.
